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Τι (ποιος) είναι cytospin cell smear - ορισμός
![herpes simplex infection]] (May-Grünwald Giemsa x1000).](https://commons.wikimedia.org/wiki/Special:FilePath/Acantholytic cell and multinucleated giant cell on a smear taken from a vesicular lesion of herpes simplex infection.jpg?width=200 "herpes simplex infection]] (May-Grünwald Giemsa x1000).")
![Extracellular and intracellular (macrophages) leishmania parasites in a patient with [[cutaneous leishmaniasis]] (May-Grünwald Giemsa x1000).](https://commons.wikimedia.org/wiki/Special:FilePath/Extracellular and intracellular leishmania parasites in a patient with cutaneous leishmaniasis.jpg?width=200 "Extracellular and intracellular (macrophages) leishmania parasites in a patient with [[cutaneous leishmaniasis]] (May-Grünwald Giemsa x1000).")
![Acantholytic cells on a smear taken from a patient with [[pemphigus foliaceus]] (May-Grünwald Giemsa x1000).](https://commons.wikimedia.org/wiki/Special:FilePath/Acantholytic cells on a smear taken from a patient with pemphigus foliaceus.jpg?width=200 "Acantholytic cells on a smear taken from a patient with [[pemphigus foliaceus]] (May-Grünwald Giemsa x1000).")
![Tadpole cells on a smear taken from a patient with allergic [[contact dermatitis]] (May-Grünwald Giemsa x1000).](https://commons.wikimedia.org/wiki/Special:FilePath/Tadpole cells on a smear taken from a patient with allergic contact dermatitis.jpg?width=200 "Tadpole cells on a smear taken from a patient with allergic [[contact dermatitis]] (May-Grünwald Giemsa x1000).")
![basal cell carcinoma]] (May-Grünwald Giemsa x1000).](https://commons.wikimedia.org/wiki/Special:FilePath/A cluster of basaloid cells on a smear taken from a patient with basal cell carcinoma.jpg?width=200 "basal cell carcinoma]] (May-Grünwald Giemsa x1000).")
!["The Great Republican Reform Party Calling on their Candidate", an 1856 political cartoon in which various "extremists", including a Catholic, press [[John C. Frémont]], the first Republican party candidate for president of the United States, for their respective causes. There was a political campaign smear rumor current in 1856 that Fremont was a Catholic.](https://commons.wikimedia.org/wiki/Special:FilePath/1856-Republican-party-Fremont-isms-caricature.jpg?width=200 "\"The Great Republican Reform Party Calling on their Candidate\", an 1856 political cartoon in which various \"extremists\", including a Catholic, press [[John C. Frémont]], the first Republican party candidate for president of the United States, for their respective causes. There was a political campaign smear rumor current in 1856 that Fremont was a Catholic.")
Βικιπαίδεια
In dermatopathology, the Tzanck test, also Tzanck smear, is scraping of an ulcer base to look for Tzanck cells. It is sometimes also called the chickenpox skin test and the herpes skin test. It is a simple, low-cost, and rapid office based test.
Tzanck cells (acantholytic cells) are found in:
- Herpes simplex
- Varicella and herpes zoster
- Pemphigus vulgaris
- Cytomegalovirus
Arnault Tzanck did the first cytological examinations in order to diagnose skin diseases. To diagnose pemphigus, he identified acantholytic cells, and to diagnose of herpetic infections he identified multinucleated giant cells and acantholytic cells. He extended his cytologic findings to certain skin tumors as well.
Even though cytological examination can provide rapid and reliable diagnosis for many skin diseases, its use is limited to a few diseases. In endemic regions, Tzanck test is used to diagnose leishmaniasis and leprosy. For other regions, Tzanck test is mainly used to diagnose pemphigus and herpetic infections. Some clinics use biopsies even for herpetic infections. This is because the advantages of this test are not well known, and the main textbooks of dermatopathology do not include dedicated sections for cytology or Tzanck smear. A deep learning model called TzanckNet has been developed to lower the experience barrier needed to use this test.
